Category: Uncategorized

Blastocyst Culture and Transfer

The growth of medical science has made it possible to achieve so many things that one could not have possibly imagined a few decades ago. The formulation of the liquid in which in vitro culture is done to grow the embryo has made it possible to grow the embryo beyond the usual 3-day time period. The embryo can now be cultured in vitro for up to 5 days until it becomes a blastocyst which is the final stage of the embryo’s development before it comes out of the egg by breaking the zona pellucida and then plant itself in the uterine wall.

Why Is It Done?

Embryo transfer on the fifth day, at the blastocyst stage, has higher pregnancy rates. There might be two conceivable explanations behind this:

Initially, transfer of the blastocyst to the uterus might be all the more physiologically suitable, since this imitates nature all the more intently, with the goal that the implantation rate might be higher. Additionally, holding up till the blastocyst stage enables the specialist to choose the best embryo since undesirable fetuses are probably going to arrest before they achieve this stage.

Blastocyst transfer fundamentally diminishes the likelihood of possibly dangerous twin or triplet birth. Higher implantation rates enable specialists to exchange fewer blastocysts – maybe just a single – decreasing or keeping away from multiple births and their related issues. Supernumerary blastocysts can likewise be effectively cryopreserved utilizing vitrification with the goal that pregnancies can be accomplished later.

Benefits Of the Blastocyst Method Over The Conventional Embryo Transfer Procedure

Previously, most embryo transfers were done on day two or day three. In any case, most great clinics have proceeded onward to doing day five (blastocyst) transfer routinely. Tragically, in India, this is as yet not the standard alternative, and a lot of IVF centers keep on transferring embryos on the second or third day. This is fundamentally in light of the fact that they’re not extremely confident about the capability of their research facility; and the capacity of their embryologist to culture eggs to day five. This is the reason they lean toward transferring the embryo into the uterus and legitimize this by telling the patient that it’s better to hatch it inside the uterus earlier. Notwithstanding, this has a considerable measure of drawbacks, and you should demand that your specialist complete a blastocyst transfer for you.

Blastocysts have a better chance of implantation, which implies the achievement rate with blastocyst transfer is higher as contrasted and Day 2 or 3 transfer. Since they’re more developed and have more cells, they have a higher probability. This additionally enables the specialist to decrease the number of embryos for transfer, so he can really exchange only maybe a couple of blastocysts and still have as great a pregnancy rate when contrasted with transferring three or four Day 3 embryos.

Additionally, since the specialist is exchanging just 1 – 2 blastocysts, you can freeze the additional blastocysts, which implies you get an opportunity to accomplish more cycles in the future. This makes it more practical in light of the fact that the total pregnancy rate goes up.

At last, the most vital reason you should demand a blastocyst transfer is that you don’t have to put yourself through that shocking 2-week hold-up of not being certain whether you will get pregnant or not on the off chance that you have low-quality embryos. Hence, if the IVF cycle flops in the wake of exchanging Day 3 embryos, you never know whether the issue was on the grounds that the fetus did not build up any further, or if there was some other explanation behind the fizzled implantation. All the more, you stay confused about whether your embryo will survive 5 days or not.

This is particularly valid for older aged women who have few eggs. Such women are at higher risk of a failed IVF since they will probably have embryos that may arrest and not reach the blastocyst age. Many of the embryos may have some genetic disorder.

These are the patients for whom a blastocyst transfer is very valuable. Nonetheless, they are frequently poor ovarian responders, and when the specialist gathers just 3-4 eggs and in this way gets not many embryos, he is exceptionally hesitant to develop them to the blastocyst stage. If it fails, the patient will point the finger at them for it. This is the reason they’d much rather transfer the embryos back in the uterus, and if the cycle fails, they can accuse this of “implantation failure”.

Notwithstanding, after the incipient organism exchange, the patient is tricked into feeling, “Admirably, perhaps this embryo may implant and grow into a baby”, which is the reason they are exceptionally confident during the waiting period. This false expectation is hurting. At the point when the cycle comes up short, they feel that it was their uterus that dismissed the embryo, and after that, they are encouraged to go down the surrogacy course. This is awful guidance which is totally imperfect on the grounds that the issue is with the egg and not with the uterus.

Shelat hospital follows an honest approach with all the patients and offers the best possible outcome in each case. This is paired with our extremely knowledgeable and experienced specialists who can help you achieve the best result in your IVF procedure. Consult with our experienced fertility specialists to know more about this procedure and discuss your options.

Birth Control And Infertility

You’ve been on birth control for more than a decade and now you’re worried that long-term use of “the pill” might harm your chances of getting pregnant in the future. Unfortunately, many misconceptions about birth control continue to circulate by word of mouth and online and we’re here to set the record straight.

CAN BIRTH CONTROL MAKE YOU INFERTILE?

Generally, the answer is no. While birth control can prevent pregnancy while you’re on it, most forms of birth control don’t harm your future fertility. It is important to know, however, that if you had irregular periods before you started birth control, those irregular cycles can return once you stop birth control.

Here’s what you need to know about different forms of birth control and how they each impact your fertility.

BIRTH CONTROL PILLS, PATCHES, AND RINGS

Birth control pills (BCP) or oral contraceptives are the most common method of contraception. Depending on the type of BCPs prescribed, they work to prevent pregnancy by impacting ovulation, causing changes to your uterine lining or cervix, or preventing sperm from fertilizing the eggs. Birth control patches and rings work similarly to the pill and your cycle should return soon after their removal.

BCPs have additional benefits that can help to preserve fertility, which includes:

• Minimize the risk of ovarian cysts
• Help relieve pain from endometriosis or prevent endometriosis from developing or getting worse
• Reduce the risk of ovarian cancer

IMPLANTS AND INJECTABLE BIRTH CONTROL

Contraceptive implants use a small flexible rod implanted in your upper arm to release progestin, a synthetic form of the hormone progesterone, which is slowly released into the body. The hormones cause the cervical mucous to thicken and thin the endometrial lining. Fertility returns within a few weeks to a month after removing the implant.

Depo-Provera, also known as the “birth control shot” or “depo shot” is given by an injection every 3 months and works by suppressing ovulation and thickening cervical mucus. Generally, most women will stop having regular periods when they are on Depo-Provera.  Once you’ve stopped taking depo shots, it can take several months to a year before your menstrual cycle resumes and allow you to conceive naturally, but it doesn’t impact your long-term fertility.

INTRAUTERINE DEVICES (IUDS)

IUDs are a highly effective and relatively safe form of birth control. Hormonal IUDs release progestin, which impacts ovulation and fertilization and many women will also stop having periods. Copper IUDs (ParaGard) contain no hormones and work by creating an inhospitable environment in the uterus preventing fertilization and implantation from taking place. IUDs and hormonal BCPs work similarly in how soon ovulation returns after stopping.

Since IUDs are inserted through the vagina into the uterus, there’s a slight risk of infection of pelvic inflammatory disease. While rare, it’s possible for an infection to spread and cause inflammation, scarring, and/or blockage in your reproductive organs, such as your fallopian tubes. Tubal scarring can block the tubes preventing the eggs from traveling to the uterus. Individuals who have damage to their fallopian tubes are also at risk for ectopic pregnancy.

BARRIER METHODS

Condoms, diaphragms, and spermicide are examples of barrier methods of birth control and don’t use hormones to prevent pregnancy. Instead, they physically block sperm from reaching the egg. Therefore, discontinuing the use of these not only poses no risk to your future fertility, but you can also begin trying to get pregnant right away.

Condoms can help protect your fertility by reducing the risk of sexually transmitted infections (STIs). If left untreated, chlamydia and gonorrhea can spread to the uterus or fallopian tubes. This can cause pelvic inflammatory disease, which can lead to inflammation, scarring, and blockage in your reproductive organs, such as your fallopian tubes.

CONTACT US

If you’re trying to get pregnant after stopping birth control and don’t conceive after a year (or six months if you’re over age 35), we recommend meeting with a fertility doctor. Make an appointment with Dr. Nimish Shelat Fertility specialist today.

The final stage of IVF is embryo transfer. Here are its dos and don’ts, as recommended by the doctors.

After an embryo transfer during IVF or in vitro fertilization, doctors once essentially advised patients to have a regular life and refrain from doing anything extra outside of their regular activities however, they no longer advise taking the rest they once did. The final stage of IVF is embryo transfer where the embryos’ capacity to implant in the uterus will determine whether IVF is successful.

If a pregnancy has occurred, the patient will need to wait roughly two weeks to find out. In other words, the process known as embryo transfer involves transferring embryos to a woman’s uterus in order to start a pregnancy and the time spent resting, following embryo transfer, was first shortened but today health experts insist that neither rest nor exercise affects or enhances the implantation rate.

1. Pamper yourself for a couple of days: Give yourself a few days to relax.

2. Relax and don’t stress: The waiting period can be a lot more stressful. De-stress and calm down your thought process.

3. Continue taking your medications on time and eat a healthy diet

4. Strictly restrict lifting heavy loads, and avoid twisting and bending post-transfer.

5. Avoid preserved foods, junk food, and spicy food: The only cause for concern is that spicy & heavy foods may increase heartburn or upset your stomach.

6. Restrict smoking cigarettes and drinking alcohol: It can lead to reduced fertilization rates, pregnancy rates, and live birth rates as well as to significantly higher chances of miscarriages or ectopic pregnancies.

7. Additionally, avoid strenuous activities such as aerobics, running, jogging, cycling, etc. Instead, you can do moderate physical activities. You may also go to work but only if your work does not involve heavy lifting or vigorous exercise.